APRIN, also known as PDS5B, is a regulator of sister chromatid cohesion in mitosis that stabilizes cohesin complex association with chromatin. It plays a crucial role in ensuring accurate chromosome partitioning in both meiotic and mitotic cells and is involved in DNA repair. APRIN also functions in androgen-induced proliferative arrest in prostate cells. This recombinant protein corresponds to a partial sequence of human APRIN, making it a valuable tool for studying chromosome cohesion, DNA repair mechanisms, and androgen signaling in prostate cells. The protein is produced in a wheat germ expression system, preserving proper folding for potential biological activity.