TG-01050
Recombinant Human AP2-associated protein kinase 1 Gly29-Lys345
Synonimy: Adaptor-associated kinase 1
AP2-associated protein kinase 1 (AAK1) is a serine/threonine protein kinase that regulates clathrin-mediated endocytosis. It phosphorylates the AP2M1 subunit of the adaptor protein complex 2, enhancing its binding to cargo membrane proteins during endocytosis. AAK1 localizes to clathrin-coated pits at the plasma membrane and presynaptic terminals in neurons. It interacts with clathrin, AP-2 complex, and NUMB, playing roles in membrane organization, Notch signaling, and protein localization. AAK1 is implicated in viral entry processes for hepatitis C, Ebola, and Dengue viruses, making it a potential target for antiviral therapies.
- TagHis-Tag
- Aktywność biologicznaNie testowano
- SpeciesHuman
- FormaLyophilizate
- ShippingAmbient
- Expression systemE. coli
- Molecular mass (kDa)36.3
- Accession numberP35156
- Przechowywanie-20°C
Informacje o zamówieniu
Dostępny:
Wysyłka do:Australia, Austria, Belgia, Brazylia, Bułgaria, Kanada, Chiny, Dania, Finlandia, Francja, Niemcy, Grecja, Węgry, Islandia, Indie, Irlandia, Włochy, Japonia, Łotwa, Holandia, Norwegia, Polska, Portugalia, Rumunia, Słowacja, Słowenia, Hiszpania, Szwecja, Szwajcaria, Zjednoczone Emiraty Arabskie, Wielka Brytania, Stany Zjednoczone
Frequently asked questions
Contact us
Didn't find what you need?
Our scientists and operation team are available to answer any questions you have. Send us a message, and a member of our team will get back to you shortly.