TG-01110
Recombinant Human GTPase KRas Thr2-Arg164
Synonimy: K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras
KRAS, a member of the RAS oncogene family, plays a critical role in intracellular signaling pathways that regulate cell proliferation and differentiation. This protein binds GDP/GTP and possesses intrinsic GTPase activity, which is important for transmitting signals from cell surface receptors. In particular, KRAS is known to be an oncogenic driver; it can induce transcriptional silencing of tumor suppressor genes in colorectal cancer cells, thus contributing to tumorigenesis. Its role in cancer biology makes KRAS a valuable target for research in therapeutics and diagnostics, especially for understanding mutations that lead to various malignancies.
- TagHis-Tag
- Aktywność biologicznaNie testowano
- SpeciesHuman
- FormaLyophilizate
- ShippingAmbient
- Expression systemE. coli
- Molecular mass (kDa)23.9
- Accession numberP01116
- Przechowywanie-20°C
Informacje o zamówieniu
Dostępny:
Wysyłka do:Australia, Austria, Belgia, Brazylia, Bułgaria, Kanada, Chiny, Dania, Finlandia, Francja, Niemcy, Grecja, Węgry, Islandia, Indie, Irlandia, Włochy, Japonia, Łotwa, Holandia, Norwegia, Polska, Portugalia, Rumunia, Słowacja, Słowenia, Hiszpania, Szwecja, Szwajcaria, Zjednoczone Emiraty Arabskie, Wielka Brytania, Stany Zjednoczone
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