AB-01160
Anti-CD28 Antibody
Synonimy: T-cell-specific surface glycoprotein CD28, TP44
This antibody targets CD28, the principal costimulatory receptor expressed on the surface of most T lymphocytes (both CD4+ and CD8+). Binding of CD28 to its ligands, CD80 (B7-1) and CD86 (B7-2), expressed on antigen-presenting cells (APCs), provides the critical "signal 2" necessary for full T cell activation, proliferation, IL-2 production, survival, and differentiation, preventing T cell anergy.
Validated for immunofluorescence, immunohistochemistry, and flow cytometry, this antibody is fundamental for studying T cell activation mechanisms, immune synapse formation, costimulatory signaling, and therapeutic strategies targeting the CD28 pathway in autoimmunity and immunotherapy.
- IsotypeIgG1
- ClonalityMonoclonal
- FormaLyophilizate
- ShippingAmbient
- Animal FreeYes
- Accession numberP10747
- Przechowywanie-20°C
Informacje o zamówieniu
Dostępny:
Wysyłka do:Australia, Austria, Belgia, Brazylia, Bułgaria, Kanada, Chiny, Dania, Finlandia, Francja, Niemcy, Grecja, Węgry, Islandia, Indie, Irlandia, Włochy, Japonia, Łotwa, Holandia, Norwegia, Polska, Portugalia, Rumunia, Słowacja, Słowenia, Hiszpania, Szwecja, Szwajcaria, Zjednoczone Emiraty Arabskie, Wielka Brytania, Stany Zjednoczone
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