AB-01137
Anti-CCR5 Antibody
Synonimy: CHEMR13, HIV-1 fusion coreceptor, CD195
This antibody targets C-C Motif Chemokine Receptor 5 (CCR5), a G protein-coupled receptor expressed primarily on Th1 T cells, memory T cells, macrophages, dendritic cells, and microglia. CCR5 binds to several chemokines, including CCL3 (MIP-1α), CCL4 (MIP-1β), and CCL5 (RANTES), mediating leukocyte trafficking to sites of inflammation. Significantly, CCR5 serves as the major co-receptor for macrophage-tropic (R5) strains of HIV-1 entry into host cells.
Validated for immunofluorescence, immunohistochemistry, and flow cytometry, this antibody allows for the identification of CCR5-expressing cells, studies on inflammatory cell recruitment, Th1 immune responses, and research into HIV-1 pathogenesis and antiviral strategies targeting viral entry.
- IsotypeIgG1
- ClonalityMonoclonal
- FormaLyophilizate
- ShippingAmbient
- Animal FreeYes
- Accession numberP51681
- Przechowywanie-20°C
Informacje o zamówieniu
Dostępny:
Wysyłka do:Australia, Austria, Belgia, Brazylia, Bułgaria, Kanada, Chiny, Dania, Finlandia, Francja, Niemcy, Grecja, Węgry, Islandia, Indie, Irlandia, Włochy, Japonia, Łotwa, Holandia, Norwegia, Polska, Portugalia, Rumunia, Słowacja, Słowenia, Hiszpania, Szwecja, Szwajcaria, Zjednoczone Emiraty Arabskie, Wielka Brytania, Stany Zjednoczone
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