Recombinant Human Ciliary Neurotrophic Factor Ala2-Met200

Ciliary Neurotrophic Factor (CNTF) is a vital neural cytokine belonging to the hematopoietic cytokine subfamily, essential for the survival and maintenance of various neuronal cell types, particularly ciliary ganglion neurons. CNTF exerts its effects by binding to a heteromeric receptor complex that activates downstream signaling pathways, including Jak and STAT transcription factors. This cytokine plays a significant role in neuroprotection, showing potential therapeutic benefits in neurodegenerative conditions such as retinitis pigmentosa, Parkinson's disease, and Huntington's disease. Its ability to prevent motor axon degeneration after axotomy highlights its importance in regenerative medicine and neurological studies, making it a critical tool for laboratory research.