TG-01086
Recombinant Human C-C motif chemokine 3 Ser24-Ala92
Synonyms: Macrophage inflammatory protein 1-alpha (MIP-1-alpha), G0/G1 switch regulatory protein 19-1, PAT 464.1, SIS-beta, Small-inducible cytokine A3, Tonsillar lymphocyte LD78 alpha protein
Recombinant Human C-C motif chemokine 3 (CCL3) is a potent inflammatory cytokine belonging to the intercrine beta (chemokine CC) family. This 69-amino acid protein functions as a monokine with inflammatory and chemokinetic properties, binding to CCR1, CCR4, and CCR5 receptors. CCL3, also known as Macrophage Inflammatory Protein 1-alpha (MIP-1-alpha), is one of the major HIV-suppressive factors produced by CD8+ T-cells, with dose-dependent inhibition of different strains of HIV-1, HIV-2, and SIV. The protein is secreted and plays crucial roles in chemotaxis, inflammatory responses, and calcium-mediated signaling. It is predominantly expressed in bone marrow, lung, and lymphoid tissues, making it a valuable target for immunological and viral research applications.
- TagHis-Tag
- Biological activityNot tested
- SpeciesHuman
- FormLyophilizate
- ShippingAmbient
- Expression systemE. coli
- Molecular mass (kDa)7.9
- Accession numberP10147
- Storage-20°C
Ordering info
Available:1 - 7 days
Shipping to:Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Denmark, Finland, France, Germany, Greece, Hungary, Iceland, India, Ireland, Italy, Japan, Latvia, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, United Arab Emirates, United Kingdom, United States
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