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TG-01046

Recombinant Human BMP-4 Ser293-Arg408

Synonyms: BMP-2B, DVR4, ZYME

Bone morphogenetic protein 4 (BMP-4) is a member of the TGF-beta superfamily of cytokines that plays essential roles in embryonic development and tissue homeostasis. It is involved in mesenchyme formation, epidermal determination, neurogenesis, angiogenesis, and osteogenesis. BMP-4 initiates signaling by binding to type I and type II serine/threonine kinase receptors, activating SMAD-dependent and independent pathways. It is crucial for stem cell differentiation, including cardiac, hematopoietic, and neural lineages. Dysregulation of BMP-4 is associated with various developmental disorders and cancers, making it an important target for research and therapeutic development.

  • TagHis-Tag
  • Biological activityNot tested
  • SpeciesHuman
  • FormLyophilizate
  • ShippingAmbient
  • Expression systemE. coli
  • Molecular mass (kDa)13.7
  • Accession numberP12644
  • Storage-20°C

Ordering info

$350.00 / 1 pc$NaNexcl. sales tax

Available:1 - 7 days

Shipping to:Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Denmark, Finland, France, Germany, Greece, Hungary, Iceland, India, Ireland, Italy, Japan, Latvia, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, United Arab Emirates, United Kingdom, United States

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