TG-01039
Recombinant Human BAFF/BLyS/TNFSF13B Ala134-Leu285
Synonyms: BLyS, TALL-1, THANK, CD257, TNFSF20, ZTNF4
B-cell activating factor (BAFF), also known as BLyS or TNFSF13B, is a 32 kDa transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) ligand superfamily. It plays a critical role in B cell development, survival, and function. BAFF is expressed by monocytes, macrophages, neutrophils, dendritic cells, and T cells. It binds to receptors BCMA, TACI, and BAFF-R on B cells, activating NF-κB signaling. BAFF promotes B cell proliferation, differentiation, and immunoglobulin production. Elevated BAFF levels are associated with autoimmune disorders and B cell malignancies. This recombinant protein can be used to study BAFF biology and as a reagent in B cell-related research.
- TagHis-Tag
- Biological activityNot tested
- SpeciesHuman
- FormLyophilizate
- ShippingAmbient
- Expression systemE. coli
- Molecular mass (kDa)17.6
- Accession numberQ9Y275
- Storage-20°C
Ordering info
Available:1 - 7 days
Shipping to:Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Denmark, Finland, France, Germany, Greece, Hungary, Iceland, India, Ireland, Italy, Japan, Latvia, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, United Arab Emirates, United Kingdom, United States
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