TG-01051
Recombinant Human ABL1 Ser229-Val515
Synonyms: c-ABL, JTK7, p150, BCR-ABL
ABL1 (Abelson murine leukemia viral oncogene homolog 1) is a non-receptor tyrosine kinase that plays a crucial role in cell growth, survival, adhesion, and motility. It participates in cytoskeleton remodeling, receptor endocytosis, autophagy, DNA damage response, and apoptosis. ABL1 phosphorylates key proteins involved in actin dynamics, cell adhesion, and signaling pathways. It is implicated in hematopoiesis, T-cell differentiation, and neuronal development. Dysregulation of ABL1 through chromosomal translocations is associated with chronic myeloid leukemia, making it an important therapeutic target in cancer research and drug development.
- TagHis-Tag
- Biological activityNot tested
- SpeciesHuman
- FormLyophilizate
- ShippingAmbient
- Expression systemE. coli
- Molecular mass (kDa)34.3
- Accession numberP00519
- Storage-20°C
Ordering info
Available:3 - 14 days
Shipping to:Canada, United States
Frequently asked questions
Contact us
Didn't find what you need?
Our scientists and operation team are available to answer any questions you have. Send us a message, and a member of our team will get back to you shortly.