Recombinant Dog Minor allergen Can f 2 Gln19-Asp180

Minor allergen Can f 2 is a salivary lipocalin protein found in dog hair and dander extracts. It belongs to the calycin superfamily and lipocalin family. Can f 2 is secreted and expressed in tongue epithelial tissue and parotid gland. This allergen plays a role in dog allergy, with sensitization associated with increased asthma severity and bronchial inflammation. Can f 2 shows limited cross-reactivity with other mammalian allergens like Fel d 4 (cat) and mouse urinary protein. As a minor allergen, it is an important component for comprehensive diagnosis of dog allergy using molecular approaches.