Recombinant Human Methionine Adenosyltransferase II, Alpha (MAT2A) Asn2-Tyr395

Methionine adenosyltransferase II, alpha (MAT2A) is an enzyme crucial for the synthesis of S-adenosylmethionine (AdoMet) from methionine and ATP, playing a vital role in methyl group transfer reactions within cells. It predominantly resides in the cytoplasm and is implicated in various biological pathways including those involved in polyamine synthesis, methylation processes, and cellular proliferation. Overexpression of MAT2A has been linked to cancer progression, making it a significant biomarker and therapeutic target. This enzyme's activity underpins vital processes, establishing its importance in both cellular metabolism and disease mechanisms for laboratory applications.