TG-01110
Recombinant Human GTPase KRas Thr2-Arg164
Synonyms: K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras
KRAS, a member of the RAS oncogene family, plays a critical role in intracellular signaling pathways that regulate cell proliferation and differentiation. This protein binds GDP/GTP and possesses intrinsic GTPase activity, which is important for transmitting signals from cell surface receptors. In particular, KRAS is known to be an oncogenic driver; it can induce transcriptional silencing of tumor suppressor genes in colorectal cancer cells, thus contributing to tumorigenesis. Its role in cancer biology makes KRAS a valuable target for research in therapeutics and diagnostics, especially for understanding mutations that lead to various malignancies.
- TagHis-Tag
- Biological activityNot tested
- SpeciesHuman
- FormLyophilizate
- ShippingAmbient
- Expression systemE. coli
- Molecular mass (kDa)23.9
- Accession numberP01116
- Storage-20°C
Ordering info
Available:1 - 7 days
Shipping to:Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Denmark, Finland, France, Germany, Greece, Hungary, Iceland, India, Ireland, Italy, Japan, Latvia, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, United Arab Emirates, United Kingdom, United States
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