AB-01034
Anti-OSMR Antibody
Synonyms: IL-31R subunit beta, IL-31R-beta, IL-31RB, OSMRB, PLCA1
This antibody specifically targets Oncostatin-M-specific receptor subunit beta (OSMR), a type I transmembrane protein that forms heterodimeric receptor complexes with IL31RA or IL6ST (gp130). OSMR plays a critical role in cytokine signaling pathways, particularly in OSM-mediated and IL-31-mediated signal transduction, activating JAK/STAT pathways including STAT3 and potentially STAT1/STAT5. The receptor is expressed in various tissues including bone marrow, liver, lung, and keratinocytes, and has been implicated in primary localized cutaneous amyloidosis.
This antibody has been validated for immunofluorescence, immunohistochemistry, and flow cytometry applications. It provides consistent and specific detection of OSMR in experimental systems.
- IsotypeIgG1
- ClonalityMonoclonal
- FormLyophilizate
- ShippingAmbient
- Animal FreeYes
- Accession numberQ99650
- Storage-20°C
Ordering info
Available:3 - 14 days
Shipping to:Canada, United States
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