AB-01038
Anti-NRF2 Antibody
Synonyms: NF-E2-related factor 2, Nuclear factor, erythroid derived 2, like 2
This antibody specifically recognizes Nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor that plays a key role in cellular response to oxidative stress. In normal conditions, Nrf2 is sequestered in the cytoplasm by KEAP1 and targeted for proteasomal degradation. Upon oxidative stress, Nrf2 translocates to the nucleus where it binds to antioxidant response elements (AREs) in promoter regions of cytoprotective genes, promoting their expression to neutralize reactive electrophiles.
This antibody has been validated for immunofluorescence, immunohistochemistry, and flow cytometry applications, making it suitable for studying Nrf2 localization and expression in various experimental contexts.
- IsotypeIgG1
- ClonalityMonoclonal
- FormLyophilizate
- ShippingAmbient
- Animal FreeYes
- Accession numberQ16236
- Storage-20°C
Ordering info
Available:3 - 14 days
Shipping to:Canada, United States
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