Anti-Laminin Antibody

This antibody specifically recognizes laminin subunit gamma-1 (LAMC1), a crucial structural component of basement membranes. LAMC1 forms heterotrimeric complexes with other laminin subunits and plays essential roles in cell attachment, migration, and organization during tissue development through interactions with extracellular matrix components. The protein is involved in multiple biological processes including cell adhesion, hemidesmosome assembly, and maintenance of the blood-brain barrier.

Validated for immunofluorescence, immunohistochemistry, and flow cytometry applications, this antibody is suitable for investigating basement membrane structure and vascular biology. The antibody enables visualization of basement membranes surrounding epithelial tissues, blood vessels, nerve, and muscle fibers.