Anti-FOXP3 Antibody

This antibody specifically targets FOXP3 (Forkhead Box P3), a critical transcriptional regulator essential for the development and functional stability of regulatory T-cells (Tregs). FOXP3 plays a pivotal role in maintaining immune system homeostasis by modulating Treg activity, inhibiting effector T-cell function, and orchestrating transcriptional programs that activate key genes such as CTLA4 and TNFRSF18 while repressing cytokine-producing genes like IL2 and IFNG. This regulatory function is fundamental for preventing autoimmunity and ensuring proper immune responses.

Our antibody has been validated for use in immunofluorescence, immunohistochemistry, and flow cytometry applications. It provides researchers with a reliable tool for investigating Treg function and immune regulation in contexts relevant to autoimmune disorders and cancer research.