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AB-01027

Anti-CtIP Antibody

Synonyms: CtBP-interacting protein (CtIP); Retinoblastoma-binding protein 8 (RBBP-8); Retinoblastoma-interacting protein and myosin-like (RIM); Sporulation in the absence of SPO11 protein 2 homolog (SAE2)

This antibody specifically targets DNA endonuclease RBBP8 (CtIP), a nuclear protein that cooperates with the MRE11-RAD50-NBN complex in DNA-end resection during double-strand break repair through the homologous recombination pathway. CtIP functions as a key determinant of DSB repair pathway choice, committing cells to homologous recombination by preventing classical non-homologous end-joining. It regulates CHEK1 activation and controls cell cycle G2/M checkpoints upon DNA damage.

Optimized for immunofluorescence, immunohistochemistry, and flow cytometry applications, this antibody enables precise detection of CtIP in experimental settings.

  • IsotypeIgG1
  • ClonalityMonoclonal
  • FormLyophilizate
  • ShippingAmbient
  • Animal FreeYes
  • Accession numberQ99708
  • Storage-20°C

Ordering info

$350.00 / 1 pc$NaNexcl. sales tax

Available:3 - 14 days

Shipping to:Canada, United States

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