AB-01027
Anti-CtIP Antibody
Synonyms: CtBP-interacting protein (CtIP); Retinoblastoma-binding protein 8 (RBBP-8); Retinoblastoma-interacting protein and myosin-like (RIM); Sporulation in the absence of SPO11 protein 2 homolog (SAE2)
This antibody specifically targets DNA endonuclease RBBP8 (CtIP), a nuclear protein that cooperates with the MRE11-RAD50-NBN complex in DNA-end resection during double-strand break repair through the homologous recombination pathway. CtIP functions as a key determinant of DSB repair pathway choice, committing cells to homologous recombination by preventing classical non-homologous end-joining. It regulates CHEK1 activation and controls cell cycle G2/M checkpoints upon DNA damage.
Optimized for immunofluorescence, immunohistochemistry, and flow cytometry applications, this antibody enables precise detection of CtIP in experimental settings.
- IsotypeIgG1
- ClonalityMonoclonal
- FormLyophilizate
- ShippingAmbient
- Animal FreeYes
- Accession numberQ99708
- Storage-20°C
Ordering info
Available:1 - 7 days
Shipping to:Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Denmark, Finland, France, Germany, Greece, Hungary, Iceland, India, Ireland, Italy, Japan, Latvia, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, United Arab Emirates, United Kingdom, United States
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