AB-01165
Anti-CDC25A Antibody
Synonyms: M-phase inducer phosphatase 1
This antibody targets Cell Division Cycle 25 Homolog A (CDC25A), a dual-specificity protein phosphatase that activates key cyclin-dependent kinases (CDKs) driving cell cycle progression. CDC25A primarily dephosphorylates and activates CDK2/Cyclin E and CDK2/Cyclin A complexes, promoting entry into and progression through S phase. Its activity is tightly regulated, and its overexpression or deregulation can lead to uncontrolled proliferation, classifying it as a proto-oncogene frequently upregulated in cancer.
Validated for immunofluorescence, immunohistochemistry, and flow cytometry applications, this antibody allows investigation into cell cycle control, G1/S transition regulation, DNA damage checkpoint responses, and the role of CDC25A in oncogenesis.
- IsotypeIgG1
- ClonalityMonoclonal
- FormLyophilizate
- ShippingAmbient
- Animal FreeYes
- Accession numberP30304
- Storage-20°C
Ordering info
Available:1 - 7 days
Shipping to:Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Denmark, Finland, France, Germany, Greece, Hungary, Iceland, India, Ireland, Italy, Japan, Latvia, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, United Arab Emirates, United Kingdom, United States
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