AB-01116
Anti-CD86 Antibody
Synonyms: Activation B7-2 antigen, B70, BU63
This antibody targets CD86, also known as B7-2. CD86 is a transmembrane protein expressed on antigen-presenting cells (APCs), including dendritic cells, macrophages, and B cells. It functions as a crucial costimulatory molecule, binding to CD28 on T cells to provide the "second signal" necessary for full T cell activation, proliferation, and cytokine production. It also binds the inhibitory receptor CTLA-4.
Validated for immunofluorescence, immunohistochemistry, and flow cytometry, this antibody is essential for studying immune cell interactions, T cell activation requirements, APC function, and modulating immune responses in contexts like vaccination, autoimmunity, and cancer immunotherapy.
- IsotypeIgG1
- ClonalityMonoclonal
- FormLyophilizate
- ShippingAmbient
- Animal FreeYes
- Accession numberP42081
- Storage-20°C
Ordering info
Available:1 - 7 days
Shipping to:Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Denmark, Finland, France, Germany, Greece, Hungary, Iceland, India, Ireland, Italy, Japan, Latvia, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, United Arab Emirates, United Kingdom, United States
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