AB-01145
Anti-CD61 Antibody
Synonyms: Integrin beta-3, Platelet membrane glycoprotein IIIa
This antibody targets CD61, also known as Integrin beta 3 (ITGB3). CD61 forms heterodimeric receptors by associating with either Integrin alpha IIb (CD41) or Integrin alpha V (CD51). The CD41/CD61 complex (GPIIb/IIIa) is highly expressed on platelets and is essential for platelet aggregation by binding fibrinogen. The CD51/CD61 complex (αvβ3 integrin) is expressed on various cells (endothelium, osteoclasts) and mediates cell adhesion, migration, and angiogenesis.
Validated for immunofluorescence, immunohistochemistry, and flow cytometry, this antibody enables the study of platelet aggregation, thrombosis, integrin signaling, angiogenesis, bone resorption, and serves as a marker for platelets and other CD61-expressing cells.
- IsotypeIgG1
- ClonalityMonoclonal
- FormLyophilizate
- ShippingAmbient
- Animal FreeYes
- Accession numberP05106
- Storage-20°C
Ordering info
Available:1 - 7 days
Shipping to:Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Denmark, Finland, France, Germany, Greece, Hungary, Iceland, India, Ireland, Italy, Japan, Latvia, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, United Arab Emirates, United Kingdom, United States
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