AB-01160
Anti-CD28 Antibody
Synonyms: T-cell-specific surface glycoprotein CD28, TP44
This antibody targets CD28, the principal costimulatory receptor expressed on the surface of most T lymphocytes (both CD4+ and CD8+). Binding of CD28 to its ligands, CD80 (B7-1) and CD86 (B7-2), expressed on antigen-presenting cells (APCs), provides the critical "signal 2" necessary for full T cell activation, proliferation, IL-2 production, survival, and differentiation, preventing T cell anergy.
Validated for immunofluorescence, immunohistochemistry, and flow cytometry, this antibody is fundamental for studying T cell activation mechanisms, immune synapse formation, costimulatory signaling, and therapeutic strategies targeting the CD28 pathway in autoimmunity and immunotherapy.
- IsotypeIgG1
- ClonalityMonoclonal
- FormLyophilizate
- ShippingAmbient
- Animal FreeYes
- Accession numberP10747
- Storage-20°C
Ordering info
Available:1 - 7 days
Shipping to:Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Denmark, Finland, France, Germany, Greece, Hungary, Iceland, India, Ireland, Italy, Japan, Latvia, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, United Arab Emirates, United Kingdom, United States
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