AB-01255
Anti-CD16 Antibody
Synonyms: Low affinity immunoglobulin gamma Fc region receptor III-A, IgG Fc receptor III-A, CD16-II
This antibody targets Fc Gamma Receptor IIIa (FCGR3A), also known as CD16a. CD16a is a low-affinity transmembrane receptor for the Fc portion of IgG antibodies, primarily expressed on Natural Killer (NK) cells, monocytes, macrophages, and subsets of T cells. Its engagement by antibody-coated target cells triggers potent effector functions, most notably Antibody-Dependent Cell-mediated Cytotoxicity (ADCC) by NK cells, and phagocytosis by macrophages. It is a key link between adaptive humoral immunity and cellular effector mechanisms.
This antibody is suitable for immunofluorescence, immunohistochemistry, and flow cytometry applications, making it crucial for identifying NK cells and monocyte/macrophage subsets, studying ADCC mechanisms, investigating humoral immune effector functions, and assessing immune responses in infection and cancer immunotherapy (e.g., related to therapeutic antibodies).
- IsotypeIgG1
- ClonalityMonoclonal
- FormLyophilizate
- ShippingAmbient
- Animal FreeYes
- Accession numberP08637
- Storage-20°C
Ordering info
Available:1 - 7 days
Shipping to:Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Denmark, Finland, France, Germany, Greece, Hungary, Iceland, India, Ireland, Italy, Japan, Latvia, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, United Arab Emirates, United Kingdom, United States
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