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AB-01263

Anti-CD117 Antibody

Synonyms: "Piebald trait protein (PBT) Proto-oncogene c-Kit Tyrosine-protein kinase Kit p145 c-kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog"

This antibody targets c-KIT (CD117), a receptor tyrosine kinase expressed on the surface of hematopoietic stem cells, mast cells, melanocytes, and interstitial cells of Cajal. c-KIT functions as the receptor for stem cell factor (SCF) and plays a pivotal role in cell proliferation, survival, migration, and differentiation across multiple lineages. It is essential in early hematopoiesis, gametogenesis, and melanogenesis, and is frequently implicated in oncogenic transformation, particularly in gastrointestinal stromal tumors (GIST) and certain leukemias.This antibody has been validated for immunofluorescence, immunohistochemistry, and flow cytometry applications, enabling investigation of stem and progenitor cell biology, tumor diagnostics, cancer stem cell markers, and signal transduction pathways in both normal and pathological contexts. It is particularly valuable for the identification and analysis of CD117-positive cell populations in developmental biology, immuno-oncology, and targeted therapy research.

  • IsotypeIgG1
  • ClonalityMonoclonal
  • FormLyophilizate
  • Shipping-20°C (dry ice)
  • Animal FreeYes
  • Accession numberP10721
  • Storage-20 degree

Ordering info

$350.00 / 1 pc$NaNexcl. sales tax

Available:1 - 7 days

Shipping to:Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Denmark, Finland, France, Germany, Greece, Hungary, Iceland, India, Ireland, Italy, Japan, Latvia, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, United Arab Emirates, United Kingdom, United States

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