AB-01137
Anti-CCR5 Antibody
Synonyms: CHEMR13, HIV-1 fusion coreceptor, CD195
This antibody targets C-C Motif Chemokine Receptor 5 (CCR5), a G protein-coupled receptor expressed primarily on Th1 T cells, memory T cells, macrophages, dendritic cells, and microglia. CCR5 binds to several chemokines, including CCL3 (MIP-1α), CCL4 (MIP-1β), and CCL5 (RANTES), mediating leukocyte trafficking to sites of inflammation. Significantly, CCR5 serves as the major co-receptor for macrophage-tropic (R5) strains of HIV-1 entry into host cells.
Validated for immunofluorescence, immunohistochemistry, and flow cytometry, this antibody allows for the identification of CCR5-expressing cells, studies on inflammatory cell recruitment, Th1 immune responses, and research into HIV-1 pathogenesis and antiviral strategies targeting viral entry.
- IsotypeIgG1
- ClonalityMonoclonal
- FormLyophilizate
- ShippingAmbient
- Animal FreeYes
- Accession numberP51681
- Storage-20°C
Ordering info
Available:1 - 7 days
Shipping to:Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Denmark, Finland, France, Germany, Greece, Hungary, Iceland, India, Ireland, Italy, Japan, Latvia, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, United Arab Emirates, United Kingdom, United States
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