AB-01444
Anti-BUB1 Antibody
Synonyms: -
This antibody targets Budding Uninhibited by Benzimidazoles 1 (BUB1), a serine/threonine kinase that is a core component of the spindle assembly checkpoint (SAC). The SAC is a critical surveillance mechanism that ensures accurate chromosome segregation by delaying anaphase onset until all chromosomes are properly attached to the mitotic spindle. BUB1 localizes to kinetochores and is essential for recruiting other SAC proteins and establishing a stable checkpoint signal.
Confirmed for use in immunofluorescence and immunohistochemistry applications, this antibody allows for the investigation of cell cycle control, mitotic progression, and the spindle assembly checkpoint. It is a key tool for studying genomic stability and the mechanisms of aneuploidy in cancer.
- IsotypeIgG1
- ClonalityMonoclonal
- FormLyophilizate
- ShippingAmbient
- Animal FreeYes
- Accession numberO43683
- Storage-20°C
Ordering info
Available:1 - 7 days
Shipping to:Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Denmark, Finland, France, Germany, Greece, Hungary, Iceland, India, Ireland, Italy, Japan, Latvia, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, United Arab Emirates, United Kingdom, United States
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