Anti-Tubulin Beta-3 Antibody

This antibody specifically targets Tubulin Beta-3 (TUBB3), a neuron-specific tubulin isotype that plays a critical role in proper axon guidance and maintenance. TUBB3 is a major constituent of microtubules, which are cytoskeletal structures composed of alpha- and beta-tubulin heterodimers. It is particularly important in neuronal development, with binding of NTN1/Netrin-1 to its receptor UNC5C influencing microtubule dynamics and axon guidance.

This antibody has been validated for immunofluorescence, immunohistochemistry, and flow cytometry applications. It serves as a reliable marker for studying neuronal cytoskeleton organization, axon development, and neuronal differentiation.