AB-01222
Anti-ATG5 Antibody
Synonyms: Autophagy protein 5, Apoptosis-specific protein
This antibody targets Autophagy Related 5 (ATG5), a protein essential for the execution of autophagy. ATG5 forms a covalent conjugate with ATG12, which then non-covalently associates with ATG16L1 to form a large E3 ubiquitin ligase-like complex. This complex is critical for mediating the lipidation of LC3 family proteins (conjugation to phosphatidylethanolamine), facilitating their incorporation into the elongating autophagosome membrane during autophagy.
This antibody is suitable for immunofluorescence, immunohistochemistry, and flow cytometry applications, making it crucial for studying the molecular machinery of autophagy, monitoring autophagosome formation, investigating cellular degradation pathways, and exploring the role of autophagy in development, disease, and stress responses.
- IsotypeIgG1
- ClonalityMonoclonal
- FormLyophilizate
- ShippingAmbient
- Animal FreeYes
- Accession numberQ9H1Y0
- Storage-20°C
Ordering info
Available:1 - 7 days
Shipping to:Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Denmark, Finland, France, Germany, Greece, Hungary, Iceland, India, Ireland, Italy, Japan, Latvia, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, United Arab Emirates, United Kingdom, United States
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