Anti-Adiponectin Antibody

This antibody specifically recognizes adiponectin (ADIPOQ), an important adipokine secreted by adipocytes that plays a critical role in metabolic regulation. Adiponectin stimulates AMPK phosphorylation in liver and skeletal muscle, enhancing glucose utilization and fatty acid oxidation while exhibiting anti-diabetic, anti-atherogenic, and anti-inflammatory properties. It functions by antagonizing TNF-alpha expression and inhibiting endothelial NF-kappa-B signaling through a cAMP-dependent pathway.

This antibody is suitable for immunofluorescence, immunohistochemistry, and flow cytometry applications. It recognizes human adiponectin and may be valuable for researchers studying obesity, type 2 diabetes, insulin resistance, and cardiovascular disease.